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Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells

BACKGROUND: Retinoblastoma is caused by loss of the Rb protein in early retinal cells. Although numerous Rb functions have been identified, Rb effects that specifically relate to the suppression of retinoblastoma have not been defined. RESULTS: In this study, we examined the effects of restoring Rb...

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Detalles Bibliográficos
Autores principales: Cobrinik, David, Francis, Richard O, Abramson, David H, Lee, Thomas C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764425/
https://www.ncbi.nlm.nih.gov/pubmed/17163992
http://dx.doi.org/10.1186/1476-4598-5-72

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