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Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells
BACKGROUND: Retinoblastoma is caused by loss of the Rb protein in early retinal cells. Although numerous Rb functions have been identified, Rb effects that specifically relate to the suppression of retinoblastoma have not been defined. RESULTS: In this study, we examined the effects of restoring Rb...
Autores principales: | Cobrinik, David, Francis, Richard O, Abramson, David H, Lee, Thomas C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764425/ https://www.ncbi.nlm.nih.gov/pubmed/17163992 http://dx.doi.org/10.1186/1476-4598-5-72 |
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