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Intermolecular Failure of L-type Ca(2+) Channel and Ryanodine Receptor Signaling in Hypertrophy

Pressure overload–induced hypertrophy is a key step leading to heart failure. The Ca(2+)-induced Ca(2+) release (CICR) process that governs cardiac contractility is defective in hypertrophy/heart failure, but the molecular mechanisms remain elusive. To examine the intermolecular aspects of CICR duri...

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Detalles Bibliográficos
Autores principales:	Xu, Ming, Zhou, Peng, Xu, Shi-Ming, Liu, Yin, Feng, Xinheng, Bai, Shu-Hua, Bai, Yan, Hao, Xue-Mei, Han, Qide, Zhang, Youyi, Wang, Shi-Qiang
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764437/ https://www.ncbi.nlm.nih.gov/pubmed/17214508 http://dx.doi.org/10.1371/journal.pbio.0050021

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