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NFAT and NFκB Activation in T Lymphocytes: A Model of Differential Activation of Gene Expression
Mathematical models for the regulation of the Ca(2+)-dependent transcription factors NFAT and NFκB that are involved in the activation of the immune and inflammatory responses in T lymphocytes have been developed. These pathways are important targets for drugs, which act as powerful immunosuppressan...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Kluwer Academic Publishers-Plenum Publishers
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764593/ https://www.ncbi.nlm.nih.gov/pubmed/17031595 http://dx.doi.org/10.1007/s10439-006-9179-4 |