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C4b Binding Protein Binds to CD154 Preventing CD40 Mediated Cholangiocyte Apoptosis: A Novel Link between Complement and Epithelial Cell Survival

Activation of CD40 on hepatocytes and cholangiocytes is critical for amplifying Fas-mediated apoptosis in the human liver. C4b-Binding Protein (C4BP) has been reported to act as a potential surrogate ligand for CD40, suggesting that it could be involved in modulating liver epithelial cell survival....

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Detalles Bibliográficos
Autores principales:	Williams, Kevin T., Young, Steven P., Negus, Alison, Young, Lawrence S., Adams, David H., Afford, Simon C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764644/ https://www.ncbi.nlm.nih.gov/pubmed/17225862 http://dx.doi.org/10.1371/journal.pone.0000159

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