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Gene expression patterns associated with p53 status in breast cancer

BACKGROUND: Breast cancer subtypes identified in genomic studies have different underlying genetic defects. Mutations in the tumor suppressor p53 occur more frequently in estrogen receptor (ER) negative, basal-like and HER2-amplified tumors than in luminal, ER positive tumors. Thus, because p53 muta...

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Detalles Bibliográficos
Autores principales: Troester, Melissa A, Herschkowitz, Jason I, Oh, Daniel S, He, Xiaping, Hoadley, Katherine A, Barbier, Claire S, Perou, Charles M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764759/
https://www.ncbi.nlm.nih.gov/pubmed/17150101
http://dx.doi.org/10.1186/1471-2407-6-276