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Dramatic tumour response to pemetrexed single-agent in an elderly patient with malignant peritoneal mesothelioma: a case report

BACKGROUND: To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options. CASE PRESENTATION: Here, we report the case of a 79-year old patient with malignant peritoneal mes...

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Detalles Bibliográficos
Autores principales: Fasola, Gianpiero, Puglisi, Fabio, Follador, Alessandro, Aita, Marianna, Di Terlizzi, Silvia, Belvedere, Ornella
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1764904/
https://www.ncbi.nlm.nih.gov/pubmed/17176466
http://dx.doi.org/10.1186/1471-2407-6-289
Descripción
Sumario:BACKGROUND: To date, there is no standard treatment for unresectable malignant peritoneal mesothelioma; either best supportive care or systemic chemotherapy with palliative intent are accepted options. CASE PRESENTATION: Here, we report the case of a 79-year old patient with malignant peritoneal mesothelioma who was treated with pemetrexed single-agent and obtained an impressive long-lasting response. CONCLUSION: Single-agent pemetrexed is a treatment option for malignant peritoneal mesothelioma in selected elderly patients or in patients with unpaired performance status.