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Prostaglandin E(2 )receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein

BACKGROUND: The pathogenesis of idiopathic Parkinson's disease (PD) remains elusive, although evidence has suggested that neuroinflammation characterized by activation of resident microglia in the brain may contribute significantly to neurodegeneration in PD. It has been demonstrated that aggre...

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Detalles Bibliográficos
Autores principales:	Jin, Jinghua, Shie, Feng-Shiun, Liu, Jun, Wang, Yan, Davis, Jeanne, Schantz, Aimee M, Montine, Kathleen S, Montine, Thomas J, Zhang, Jing
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766347/ https://www.ncbi.nlm.nih.gov/pubmed/17204153 http://dx.doi.org/10.1186/1742-2094-4-2

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