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Regional age-related changes in neuronal nitric oxide synthase (nNOS), messenger RNA levels and activity in SAMP8 brain

BACKGROUND: Nitric oxide (NO) is a multifunctional molecule synthesized by three isozymes of the NO synthase (NOSs) acting as a messenger/modulator and/or a potential neurotoxin. In rodents, the role of NOSs in sleep processes and throughout aging is now well established. For example, sleep paramete...

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Detalles Bibliográficos
Autores principales: Colas, Damien, Gharib, Abdallah, Bezin, Laurent, Morales, Anne, Guidon, Gérard, Cespuglio, Raymond, Sarda, Nicole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1766358/
https://www.ncbi.nlm.nih.gov/pubmed/17184520
http://dx.doi.org/10.1186/1471-2202-7-81