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Intracerebral administration of Interleukin-12 (IL-12) and IL-18 modifies the course of mouse scrapie

BACKGROUND: Prion diseases are characterised by a neurodegenerative pattern in which the function of immune system remains still elusive. In the present study, we evaluate if an exogenous treatment with Interleukin-12 (IL-12) and IL-18, able to activate microglia, is able to affect scrapie pathogene...

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Detalles Bibliográficos
Autores principales:	Pasquali, Paolo, Nonno, Romolo, Mandara, Maria Teresa, Di Bari, Michele Angelo, Ricci, Giovanni, Petrucci, Paola, Capuccini, Silvia, Cartoni, Claudia, Macrì, Agostino, Agrimi, Umberto
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1769363/ https://www.ncbi.nlm.nih.gov/pubmed/17192191 http://dx.doi.org/10.1186/1746-6148-2-37

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