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Logarithmic gap costs decrease alignment accuracy

BACKGROUND: Studies on the distribution of indel sizes have consistently found that they obey a power law. This finding has lead several scientists to propose that logarithmic gap costs, G (k) = a + c ln k, are more biologically realistic than affine gap costs, G (k) = a + bk, for sequence alignment...

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Detalles Bibliográficos
Autor principal: Cartwright, Reed A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770940/
https://www.ncbi.nlm.nih.gov/pubmed/17147805
http://dx.doi.org/10.1186/1471-2105-7-527