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Logarithmic gap costs decrease alignment accuracy
BACKGROUND: Studies on the distribution of indel sizes have consistently found that they obey a power law. This finding has lead several scientists to propose that logarithmic gap costs, G (k) = a + c ln k, are more biologically realistic than affine gap costs, G (k) = a + bk, for sequence alignment...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770940/ https://www.ncbi.nlm.nih.gov/pubmed/17147805 http://dx.doi.org/10.1186/1471-2105-7-527 |