Acute leukaemoid reaction following cardiac surgery

Chronic myelomonocytic leukaemia is an atypical myeloproliferative disorder with a natural history of progression to acute myeloid leukaemia, a complex and poorly understood response by the bone marrow to stress. Cardiac surgery activates many inflammatory cascades and may precipitate a systemic inf...

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Detalles Bibliográficos
Autores principales: Drury, Nigel E, Ali, Ayyaz, Mussa, Shafi, Webb, Stephen T, Rege, Kanchan P, Wallwork, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774565/
https://www.ncbi.nlm.nih.gov/pubmed/17212818
http://dx.doi.org/10.1186/1749-8090-2-3
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author Drury, Nigel E
Ali, Ayyaz
Mussa, Shafi
Webb, Stephen T
Rege, Kanchan P
Wallwork, John
author_facet Drury, Nigel E
Ali, Ayyaz
Mussa, Shafi
Webb, Stephen T
Rege, Kanchan P
Wallwork, John
author_sort Drury, Nigel E
collection PubMed
description Chronic myelomonocytic leukaemia is an atypical myeloproliferative disorder with a natural history of progression to acute myeloid leukaemia, a complex and poorly understood response by the bone marrow to stress. Cardiac surgery activates many inflammatory cascades and may precipitate a systemic inflammatory response syndrome. We present a case of undiagnosed chronic myelomonocytic leukaemia who developed rapidly fatal multi-organ dysfunction following cardiac surgery due to an acute leukaemoid reaction.
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spelling pubmed-17745652007-01-18 Acute leukaemoid reaction following cardiac surgery Drury, Nigel E Ali, Ayyaz Mussa, Shafi Webb, Stephen T Rege, Kanchan P Wallwork, John J Cardiothorac Surg Case Report Chronic myelomonocytic leukaemia is an atypical myeloproliferative disorder with a natural history of progression to acute myeloid leukaemia, a complex and poorly understood response by the bone marrow to stress. Cardiac surgery activates many inflammatory cascades and may precipitate a systemic inflammatory response syndrome. We present a case of undiagnosed chronic myelomonocytic leukaemia who developed rapidly fatal multi-organ dysfunction following cardiac surgery due to an acute leukaemoid reaction. BioMed Central 2007-01-09 /pmc/articles/PMC1774565/ /pubmed/17212818 http://dx.doi.org/10.1186/1749-8090-2-3 Text en Copyright © 2007 Drury et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Drury, Nigel E
Ali, Ayyaz
Mussa, Shafi
Webb, Stephen T
Rege, Kanchan P
Wallwork, John
Acute leukaemoid reaction following cardiac surgery
title Acute leukaemoid reaction following cardiac surgery
title_full Acute leukaemoid reaction following cardiac surgery
title_fullStr Acute leukaemoid reaction following cardiac surgery
title_full_unstemmed Acute leukaemoid reaction following cardiac surgery
title_short Acute leukaemoid reaction following cardiac surgery
title_sort acute leukaemoid reaction following cardiac surgery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774565/
https://www.ncbi.nlm.nih.gov/pubmed/17212818
http://dx.doi.org/10.1186/1749-8090-2-3
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AT webbstephent acuteleukaemoidreactionfollowingcardiacsurgery
AT regekanchanp acuteleukaemoidreactionfollowingcardiacsurgery
AT wallworkjohn acuteleukaemoidreactionfollowingcardiacsurgery

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