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SIV(SM)/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells

BACKGROUND: Vpx is a non-structural protein coded by members of the SIV(SM)/HIV-2 lineage that is believed to have originated by duplication of the common vpr gene present in primate lentiviruses. Vpx is incorporated into virion particles and is thus present during the early steps of viral infection...

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Detalles Bibliográficos
Autores principales: Goujon, Caroline, Rivière, Lise, Jarrosson-Wuilleme, Loraine, Bernaud, Jeanine, Rigal, Dominique, Darlix, Jean-Luc, Cimarelli, Andrea
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779362/
https://www.ncbi.nlm.nih.gov/pubmed/17212817
http://dx.doi.org/10.1186/1742-4690-4-2