Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice

Professional antigen-presenting cells, such as dendritic cells, macrophages and B cells have been implicated in the pathogenesis of rheumatoid arthritis, constituting a possible target for antigen-specific immunotherapy. We addressed the possibility of blocking antigen presentation of the type II co...

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Detalles Bibliográficos
Autores principales: von Delwig, Alexei, Hilkens, Catharien MU, Altmann, Daniel M, Holmdahl, Rikard, Isaacs, John D, Harding, Clifford V, Robertson, Helen, McKie, Norman, Robinson, John H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779380/
https://www.ncbi.nlm.nih.gov/pubmed/16704744
http://dx.doi.org/10.1186/ar1964

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