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A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis
Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and destruction of cartilage and bone. The fibroblast-like synoviocyte (FLS) population is central to the development of pannus by migrating into cartilage and bone. We demonstrated previously that expression of the cell cycle inhibi...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779389/ https://www.ncbi.nlm.nih.gov/pubmed/16846525 http://dx.doi.org/10.1186/ar1999 |