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Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene

Knee osteoarthritis (OA) results, at least in part, from overloading and inflammation leading to cartilage degradation. Prostaglandin E2 (PGE(2)) is one of the main catabolic factors involved in OA. Its synthesis is the result of cyclooxygenase (COX) and prostaglandin E synthase (PGES) activities wh...

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Detalles Bibliográficos
Autores principales:	Gosset, Marjolaine, Berenbaum, Francis, Levy, Arlette, Pigenet, Audrey, Thirion, Sylvie, Saffar, Jean-Louis, Jacques, Claire
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779392/ https://www.ncbi.nlm.nih.gov/pubmed/16872525 http://dx.doi.org/10.1186/ar2024

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