Local treatment with the selective IκB kinase β inhibitor NEMO-binding domain peptide ameliorates synovial inflammation

Nuclear factor (NF)-κB is a key regulator of synovial inflammation. We investigated the effect of local NF-κB inhibition in rat adjuvant arthritis (AA), using the specific IκB kinase (IKK)-β blocking NF-κB essential modulator-binding domain (NBD) peptide. The effects of the NBD peptide on human fibr...

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Detalles Bibliográficos
Autores principales: Tas, Sander W, Vervoordeldonk, Margriet J, Hajji, Najat, May, Michael J, Ghosh, Sankar, Tak, Paul P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779420/
https://www.ncbi.nlm.nih.gov/pubmed/16684367
http://dx.doi.org/10.1186/ar1958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779420/
https://www.ncbi.nlm.nih.gov/pubmed/16684367
http://dx.doi.org/10.1186/ar1958

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