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Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-β signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer p...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779470/ https://www.ncbi.nlm.nih.gov/pubmed/16834786 http://dx.doi.org/10.1186/bcr1520 |
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author | Grimm, Sandra L Rosen, Jeffrey M |
author_facet | Grimm, Sandra L Rosen, Jeffrey M |
author_sort | Grimm, Sandra L |
collection | PubMed |
description | Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-β signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression. |
format | Text |
id | pubmed-1779470 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-17794702007-01-19 Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating Grimm, Sandra L Rosen, Jeffrey M Breast Cancer Res Commentary Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-β signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression. BioMed Central 2006 2006-07-11 /pmc/articles/PMC1779470/ /pubmed/16834786 http://dx.doi.org/10.1186/bcr1520 Text en Copyright © 2006 BioMed Central Ltd |
spellingShingle | Commentary Grimm, Sandra L Rosen, Jeffrey M Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
title | Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
title_full | Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
title_fullStr | Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
title_full_unstemmed | Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
title_short | Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
title_sort | stop! in the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779470/ https://www.ncbi.nlm.nih.gov/pubmed/16834786 http://dx.doi.org/10.1186/bcr1520 |
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