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Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating

Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-β signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer p...

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Detalles Bibliográficos
Autores principales: Grimm, Sandra L, Rosen, Jeffrey M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779470/
https://www.ncbi.nlm.nih.gov/pubmed/16834786
http://dx.doi.org/10.1186/bcr1520
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author Grimm, Sandra L
Rosen, Jeffrey M
author_facet Grimm, Sandra L
Rosen, Jeffrey M
author_sort Grimm, Sandra L
collection PubMed
description Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-β signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression.
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spelling pubmed-17794702007-01-19 Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating Grimm, Sandra L Rosen, Jeffrey M Breast Cancer Res Commentary Recent genetic and cell biological studies illustrate the importance of active transforming growth factor-β signaling in preventing the proliferation of estrogen receptor-positive cells in the normal mammary gland, and suggest how the loss of this inhibition may be important in early breast cancer progression. BioMed Central 2006 2006-07-11 /pmc/articles/PMC1779470/ /pubmed/16834786 http://dx.doi.org/10.1186/bcr1520 Text en Copyright © 2006 BioMed Central Ltd
spellingShingle Commentary
Grimm, Sandra L
Rosen, Jeffrey M
Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
title Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
title_full Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
title_fullStr Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
title_full_unstemmed Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
title_short Stop! In the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
title_sort stop! in the name of transforming growth factor-β: keeping estrogen receptor-α-positive mammary epithelial cells from proliferating
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779470/
https://www.ncbi.nlm.nih.gov/pubmed/16834786
http://dx.doi.org/10.1186/bcr1520
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