Fine-Tuning Reception in the Bone: PPARγ and Company

PPARγ plays a central role in the formation of fat. Regulation of PPARγ activity depends on numerous factors ranging from dietary ligands to nuclear hormone coactivators and corepressors to oxygen-sensing mechanisms. In addition, the interplay of PPARγ with other nuclear hormone receptors has implic...

Descripción completa

Detalles Bibliográficos
Autores principales: Floyd, Z. Elizabeth, Zvonic, Sanjin, E. Nuttall, Mark, M. Gimble, Jeffrey
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779576/
https://www.ncbi.nlm.nih.gov/pubmed/17259665
http://dx.doi.org/10.1155/PPAR/2006/52950
_version_ 1782131808392970240
author Floyd, Z. Elizabeth
Zvonic, Sanjin
E. Nuttall, Mark
M. Gimble, Jeffrey
author_facet Floyd, Z. Elizabeth
Zvonic, Sanjin
E. Nuttall, Mark
M. Gimble, Jeffrey
author_sort Floyd, Z. Elizabeth
collection PubMed
description PPARγ plays a central role in the formation of fat. Regulation of PPARγ activity depends on numerous factors ranging from dietary ligands to nuclear hormone coactivators and corepressors to oxygen-sensing mechanisms. In addition, the interplay of PPARγ with other nuclear hormone receptors has implications for the balance between adipogenesis and osteogenesis in mesenchymal stem cells of the bone marrow stroma. This review will explore a range of factors influencing PPARγ activity and how these interactions may affect osteogenesis.
format Text
id pubmed-1779576
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-17795762007-02-01 Fine-Tuning Reception in the Bone: PPARγ and Company Floyd, Z. Elizabeth Zvonic, Sanjin E. Nuttall, Mark M. Gimble, Jeffrey PPAR Res Review Article PPARγ plays a central role in the formation of fat. Regulation of PPARγ activity depends on numerous factors ranging from dietary ligands to nuclear hormone coactivators and corepressors to oxygen-sensing mechanisms. In addition, the interplay of PPARγ with other nuclear hormone receptors has implications for the balance between adipogenesis and osteogenesis in mesenchymal stem cells of the bone marrow stroma. This review will explore a range of factors influencing PPARγ activity and how these interactions may affect osteogenesis. Hindawi Publishing Corporation 2006 2006-08-01 /pmc/articles/PMC1779576/ /pubmed/17259665 http://dx.doi.org/10.1155/PPAR/2006/52950 Text en Copyright © 2006 Z. Elizabeth Floyd et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Floyd, Z. Elizabeth
Zvonic, Sanjin
E. Nuttall, Mark
M. Gimble, Jeffrey
Fine-Tuning Reception in the Bone: PPARγ and Company
title Fine-Tuning Reception in the Bone: PPARγ and Company
title_full Fine-Tuning Reception in the Bone: PPARγ and Company
title_fullStr Fine-Tuning Reception in the Bone: PPARγ and Company
title_full_unstemmed Fine-Tuning Reception in the Bone: PPARγ and Company
title_short Fine-Tuning Reception in the Bone: PPARγ and Company
title_sort fine-tuning reception in the bone: pparγ and company
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779576/
https://www.ncbi.nlm.nih.gov/pubmed/17259665
http://dx.doi.org/10.1155/PPAR/2006/52950
work_keys_str_mv AT floydzelizabeth finetuningreceptionintheboneppargandcompany
AT zvonicsanjin finetuningreceptionintheboneppargandcompany
AT enuttallmark finetuningreceptionintheboneppargandcompany
AT mgimblejeffrey finetuningreceptionintheboneppargandcompany

Ejemplares similares