UniPep - a database for human N-linked glycosites: a resource for biomarker discovery

There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Loriaux, Paul, Eng, Jimmy, Campbell, David, Keller, Andrew, Moss, Pat, Bonneau, Richard, Zhang, Ning, Zhou, Yong, Wollscheid, Bernd, Cooke, Kelly, Yi, Eugene C, Lee, Hookeun, Peskind, Elaine R, Zhang, Jing, Smith, Richard D, Aebersold, Ruedi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779586/
https://www.ncbi.nlm.nih.gov/pubmed/16901351
http://dx.doi.org/10.1186/gb-2006-7-8-r73
Descripción
Sumario:There has been considerable recent interest in proteomic analyses of plasma for the purpose of discovering biomarkers. Profiling N-linked glycopeptides is a particularly promising method because the population of N-linked glycosites represents the proteomes of plasma, the cell surface, and secreted proteins at very low redundancy and provides a compelling link between the tissue and plasma proteomes. Here, we describe UniPep - a database of human N-linked glycosites - as a resource for biomarker discovery.

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