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Hmgcr in the Corpus Allatum Controls Sexual Dimorphism of Locomotor Activity and Body Size via the Insulin Pathway in Drosophila
The insulin signaling pathway has been implicated in several physiological and developmental processes. In mammals, it controls expression of 3-Hydroxy-3-Methylglutaryl CoA Reductase (HMGCR), a key enzyme in cholesterol biosynthesis. In insects, which can not synthesize cholesterol de novo, the HMGC...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779623/ https://www.ncbi.nlm.nih.gov/pubmed/17264888 http://dx.doi.org/10.1371/journal.pone.0000187 |