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On the Action of Methotrexate and 6-Mercaptopurine on M. avium Subspecies paratuberculosis

BACKGROUND: Clinical improvement in inflammatory bowel disease (IBD) treated with methotrexate and 6-mercaptopurine (6-MP) is associated with a decrease in pro-inflammatory cytokines. This has been presumed to indicate the mechanism of action of methotrexate and 6-MP. Although controversial, there a...

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Detalles Bibliográficos
Autores principales: Greenstein, Robert J., Su, Liya, Haroutunian, Vahram, Shahidi, Azra, Brown, Sheldon T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779805/
https://www.ncbi.nlm.nih.gov/pubmed/17252054
http://dx.doi.org/10.1371/journal.pone.0000161