The Architecture of the Adhesive Apparatus of Cultured Osteoclasts: From Podosome Formation to Sealing Zone Assembly

BACKGROUND: Osteoclasts are bone-degrading cells, which play a central role in physiological bone remodeling. Unbalanced osteoclast activity is largely responsible for pathological conditions such as osteoporosis. Osteoclasts develop specialized adhesion structures, the so-called podosomes, which su...

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Detalles Bibliográficos
Autores principales: Luxenburg, Chen, Geblinger, Dafna, Klein, Eugenia, Anderson, Karen, Hanein, Dorit, Geiger, Benny, Addadi, Lia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779809/
https://www.ncbi.nlm.nih.gov/pubmed/17264882
http://dx.doi.org/10.1371/journal.pone.0000179

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