Apical Localization of Sodium-Dependent Glucose Transporter SGLT1 is Maintained by Cholesterol and Microtubules

A GFP-labeled sodium-dependent glucose transporter SGLT1 (SGLT-GFP) was transfected into MDCK cells. SGLT-GFP was localized at the apical membrane in confluent cells. When cellular cholesterol was depleted by methyl-β-cyclodextrin (MβCD) treatment, the localization of SGLT-GFP gradually switched fro...

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Detalles Bibliográficos
Autores principales: Suzuki, Takeshi, Matsuzaki, Toshiyuki, Hagiwara, Haruo, Aoki, Takeo, Tajika-Takahashi, Yukiko, Takata, Kuniaki
Formato: Texto
Lenguaje:English
Publicado: Japan Society of Histochemistry and Cytochemistry 2006
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779948/
https://www.ncbi.nlm.nih.gov/pubmed/17327902
http://dx.doi.org/10.1267/ahc.06024

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