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Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine

BACKGROUND: Cell culture systems are useful in studying toxicological effects of chemicals such as Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), however little is known as to how accurately isolated cells reflect responses of intact organs. In this work, we compare transcriptional responses in live...

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Detalles Bibliográficos
Autores principales:	Perkins, Edward J, Bao, Wenjun, Guan, Xin, Ang, Choo-Yaw, Wolfinger, Russell D, Chu, Tzu-Ming, Meyer, Sharon A, Inouye, Laura S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780121/ https://www.ncbi.nlm.nih.gov/pubmed/17217515 http://dx.doi.org/10.1186/1471-2105-7-S4-S22

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