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Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis

The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining region of the rearranged heavy chain variable region gene) length as a marker. A modified immunoglobulin V(H) gene fingerprinting met...

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Detalles Bibliográficos
Autores principales: Itoh, Kenji, Patki, Varsha, Furie, Richard A, Chartash, Elliot K, Jain, Rita I, Lane, Lewis, Asnis, Stanley E, Chiorazzi, Nicholas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17803/
https://www.ncbi.nlm.nih.gov/pubmed/11219389