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Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis
The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining region of the rearranged heavy chain variable region gene) length as a marker. A modified immunoglobulin V(H) gene fingerprinting met...
Autores principales: | Itoh, Kenji, Patki, Varsha, Furie, Richard A, Chartash, Elliot K, Jain, Rita I, Lane, Lewis, Asnis, Stanley E, Chiorazzi, Nicholas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17803/ https://www.ncbi.nlm.nih.gov/pubmed/11219389 |
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