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High glucose upregulates connective tissue growth factor expression in human vascular smooth muscle cells

BACKGROUND: Connective tissue growth factor (CTGF) is a potent profibrotic factor, which is implicated in fibroblast proliferation, angiogenesis and extracellular matrix (ECM) synthesis. It is a downstream mediator of some of the effects of transforming growth factor β (TGFβ) and is potentially indu...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaojing, Luo, Fengming, Pan, Kejian, Wu, Wenchao, Chen, Huaiqing
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781444/ https://www.ncbi.nlm.nih.gov/pubmed/17224075 http://dx.doi.org/10.1186/1471-2121-8-1

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