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Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells

Epigenetic silencing of regulatory genes by aberrant methylation contributes to tumorigenesis. DNA methyltransferase inhibitors (DNMTI) represent promising new drugs for anti-cancer therapies. The DNMTI 5-Azacytidine is effective against myelodysplastic syndrome, but induces switching of latent to l...

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Detalles Bibliográficos
Autores principales:	Rao, Sieta P, Rechsteiner, Markus P, Berger, Christoph, Sigrist, Jürg A, Nadal, David, Bernasconi, Michele
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781464/ https://www.ncbi.nlm.nih.gov/pubmed/17214905 http://dx.doi.org/10.1186/1476-4598-6-3

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