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ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially
BACKGROUND: The mitogen-activated protein (MAP) kinases p44(ERK1 )and p42(ERK2 )are crucial components of the regulatory machinery underlying normal and malignant cell proliferation. A currently accepted model maintains that ERK1 and ERK2 are regulated similarly and contribute to intracellular signa...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781522/ https://www.ncbi.nlm.nih.gov/pubmed/16805921 http://dx.doi.org/10.1186/jbiol38 |