Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.

This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients. In contrast, plasma levels of two enzymatic activities, one implicated in PAF production (i.e. phospholipase A2) and one in PAF degradation (i...

Descripción completa

Detalles Bibliográficos
Autores principales: Denizot, Yves, Truffinet, Véronique, Bouvier, Stéphane, Gainant, Alain, Cubertafond, Pierre, Mathonnet, Muriel
Formato: Texto
Lenguaje:English
Publicado: 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781534/
https://www.ncbi.nlm.nih.gov/pubmed/15203567
http://dx.doi.org/10.1080/09629350410001664824
_version_ 1782131895258054656
author Denizot, Yves
Truffinet, Véronique
Bouvier, Stéphane
Gainant, Alain
Cubertafond, Pierre
Mathonnet, Muriel
author_facet Denizot, Yves
Truffinet, Véronique
Bouvier, Stéphane
Gainant, Alain
Cubertafond, Pierre
Mathonnet, Muriel
author_sort Denizot, Yves
collection PubMed
description This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients. In contrast, plasma levels of two enzymatic activities, one implicated in PAF production (i.e. phospholipase A2) and one in PAF degradation (i.e. PAF acetylhydrolase activity) were significantly elevated.
format Text
id pubmed-1781534
institution National Center for Biotechnology Information
language English
publishDate 2004
record_format MEDLINE/PubMed
spelling pubmed-17815342007-01-25 Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer. Denizot, Yves Truffinet, Véronique Bouvier, Stéphane Gainant, Alain Cubertafond, Pierre Mathonnet, Muriel Mediators Inflamm Research Article This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients. In contrast, plasma levels of two enzymatic activities, one implicated in PAF production (i.e. phospholipase A2) and one in PAF degradation (i.e. PAF acetylhydrolase activity) were significantly elevated. 2004-02 /pmc/articles/PMC1781534/ /pubmed/15203567 http://dx.doi.org/10.1080/09629350410001664824 Text en
spellingShingle Research Article
Denizot, Yves
Truffinet, Véronique
Bouvier, Stéphane
Gainant, Alain
Cubertafond, Pierre
Mathonnet, Muriel
Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
title Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
title_full Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
title_fullStr Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
title_full_unstemmed Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
title_short Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
title_sort elevated plasma phospholipase a2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781534/
https://www.ncbi.nlm.nih.gov/pubmed/15203567
http://dx.doi.org/10.1080/09629350410001664824
work_keys_str_mv AT denizotyves elevatedplasmaphospholipasea2andplateletactivatingfactoracetylhydrolaseactivityincolorectalcancer
AT truffinetveronique elevatedplasmaphospholipasea2andplateletactivatingfactoracetylhydrolaseactivityincolorectalcancer
AT bouvierstephane elevatedplasmaphospholipasea2andplateletactivatingfactoracetylhydrolaseactivityincolorectalcancer
AT gainantalain elevatedplasmaphospholipasea2andplateletactivatingfactoracetylhydrolaseactivityincolorectalcancer
AT cubertafondpierre elevatedplasmaphospholipasea2andplateletactivatingfactoracetylhydrolaseactivityincolorectalcancer
AT mathonnetmuriel elevatedplasmaphospholipasea2andplateletactivatingfactoracetylhydrolaseactivityincolorectalcancer

Ejemplares similares