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Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax.
The aim of the present study is to determine whether patients with primary spontaneous pneumothorax (PSP) are subject to oxidative stress. For this purpose, we measured the activities of red blood cell superoxide dismutase, which is an antioxidant enzyme, and the level of plasma malondialdehyde, whi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781553/ https://www.ncbi.nlm.nih.gov/pubmed/15223614 http://dx.doi.org/10.1080/09511920410001713475 |
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author | Tabakoglu, Erhan Ciftci, Senturk Hatipoglu, Osman Nuri Altiay, Gündeniz Caglar, Tuncay |
author_facet | Tabakoglu, Erhan Ciftci, Senturk Hatipoglu, Osman Nuri Altiay, Gündeniz Caglar, Tuncay |
author_sort | Tabakoglu, Erhan |
collection | PubMed |
description | The aim of the present study is to determine whether patients with primary spontaneous pneumothorax (PSP) are subject to oxidative stress. For this purpose, we measured the activities of red blood cell superoxide dismutase, which is an antioxidant enzyme, and the level of plasma malondialdehyde, which is one of the lipid peroxidation markers, in a group of patients with PSP. The study was carried out with 16 patients with PSP and 24 healthy individuals. The two groups were similar to each other in terms of sex, age and smoking attitudes. Erythrocyte superoxide dismutase activity was found to be significantly lower in patients with PSP than in the control group (p < 0.01). The plasma malondialdehyde levels were significantly high in patients with PSP (p < 0.01). Our results suggest that oxidative stress may contribute to the pathogenesis of PSP. |
format | Text |
id | pubmed-1781553 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
record_format | MEDLINE/PubMed |
spelling | pubmed-17815532007-01-25 Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. Tabakoglu, Erhan Ciftci, Senturk Hatipoglu, Osman Nuri Altiay, Gündeniz Caglar, Tuncay Mediators Inflamm Research Article The aim of the present study is to determine whether patients with primary spontaneous pneumothorax (PSP) are subject to oxidative stress. For this purpose, we measured the activities of red blood cell superoxide dismutase, which is an antioxidant enzyme, and the level of plasma malondialdehyde, which is one of the lipid peroxidation markers, in a group of patients with PSP. The study was carried out with 16 patients with PSP and 24 healthy individuals. The two groups were similar to each other in terms of sex, age and smoking attitudes. Erythrocyte superoxide dismutase activity was found to be significantly lower in patients with PSP than in the control group (p < 0.01). The plasma malondialdehyde levels were significantly high in patients with PSP (p < 0.01). Our results suggest that oxidative stress may contribute to the pathogenesis of PSP. 2004-06 /pmc/articles/PMC1781553/ /pubmed/15223614 http://dx.doi.org/10.1080/09511920410001713475 Text en |
spellingShingle | Research Article Tabakoglu, Erhan Ciftci, Senturk Hatipoglu, Osman Nuri Altiay, Gündeniz Caglar, Tuncay Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
title | Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
title_full | Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
title_fullStr | Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
title_full_unstemmed | Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
title_short | Levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
title_sort | levels of superoxide dismutase and malondialdehyde in primary spontaneous pneumothorax. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781553/ https://www.ncbi.nlm.nih.gov/pubmed/15223614 http://dx.doi.org/10.1080/09511920410001713475 |
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