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No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response. AIM: The hypothesis was verified as to whether ozonated autohemotherapy using an ozone dose in therapeutic range changes the plasma concentration of C-reactive protein and interleukin-6, markers of inflammation. METHODS: In a...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781578/ https://www.ncbi.nlm.nih.gov/pubmed/15770057 http://dx.doi.org/10.1155/S0962935104000572 |
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author | Tylicki, Leszek Biedunkiewicz, Bogdan Rachon, Dominik Nieweglowski, Tomasz Hak, Lukasz Chamienia, Andrzej Debska-Slizien, Alicja Aleksandrowicz, Ewa Mysliwska, Jolanta Rutkowski, Boleslaw |
author_facet | Tylicki, Leszek Biedunkiewicz, Bogdan Rachon, Dominik Nieweglowski, Tomasz Hak, Lukasz Chamienia, Andrzej Debska-Slizien, Alicja Aleksandrowicz, Ewa Mysliwska, Jolanta Rutkowski, Boleslaw |
author_sort | Tylicki, Leszek |
collection | PubMed |
description | BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response. AIM: The hypothesis was verified as to whether ozonated autohemotherapy using an ozone dose in therapeutic range changes the plasma concentration of C-reactive protein and interleukin-6, markers of inflammation. METHODS: In a controlled, single-blind, cross-over study, 12 chronically hemodialyzed patients with peripheral arterial disease were exposed to nine sessions of autohemotherapy with blood exposure to oxygen as a control followed by nine sessions of ozonated autohemotherapy with an ozone concentration of 50 microg/ml. RESULTS: There was no statistical difference between C-reactive protein levels at baseline (1.53 +/- 1.01 mg/l), after nine sessions of control autohemotherapy (1.48 +/- 0.96 mg/l), and after nine sessions of ozonated autohemotherapy (1.55 +/- 0.84 mg/l). There was also no statistical difference between the interleukin-6 serum concentration at baseline (438 +/- 118 pg/ml), after nine sessions of control autohemotherapy (444 +/- 120 pg/ml), and after nine sessions of ozonated autohemotherapy (466 +/- 152 pg/ml). CONCLUSION: The results of this study suggest that ozonated autohemotherapy using an ozone concentration of 50 microg/ml does not induce an inflammatory response. |
format | Text |
id | pubmed-1781578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
record_format | MEDLINE/PubMed |
spelling | pubmed-17815782007-01-25 No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. Tylicki, Leszek Biedunkiewicz, Bogdan Rachon, Dominik Nieweglowski, Tomasz Hak, Lukasz Chamienia, Andrzej Debska-Slizien, Alicja Aleksandrowicz, Ewa Mysliwska, Jolanta Rutkowski, Boleslaw Mediators Inflamm Research Article BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response. AIM: The hypothesis was verified as to whether ozonated autohemotherapy using an ozone dose in therapeutic range changes the plasma concentration of C-reactive protein and interleukin-6, markers of inflammation. METHODS: In a controlled, single-blind, cross-over study, 12 chronically hemodialyzed patients with peripheral arterial disease were exposed to nine sessions of autohemotherapy with blood exposure to oxygen as a control followed by nine sessions of ozonated autohemotherapy with an ozone concentration of 50 microg/ml. RESULTS: There was no statistical difference between C-reactive protein levels at baseline (1.53 +/- 1.01 mg/l), after nine sessions of control autohemotherapy (1.48 +/- 0.96 mg/l), and after nine sessions of ozonated autohemotherapy (1.55 +/- 0.84 mg/l). There was also no statistical difference between the interleukin-6 serum concentration at baseline (438 +/- 118 pg/ml), after nine sessions of control autohemotherapy (444 +/- 120 pg/ml), and after nine sessions of ozonated autohemotherapy (466 +/- 152 pg/ml). CONCLUSION: The results of this study suggest that ozonated autohemotherapy using an ozone concentration of 50 microg/ml does not induce an inflammatory response. 2004-12 /pmc/articles/PMC1781578/ /pubmed/15770057 http://dx.doi.org/10.1155/S0962935104000572 Text en |
spellingShingle | Research Article Tylicki, Leszek Biedunkiewicz, Bogdan Rachon, Dominik Nieweglowski, Tomasz Hak, Lukasz Chamienia, Andrzej Debska-Slizien, Alicja Aleksandrowicz, Ewa Mysliwska, Jolanta Rutkowski, Boleslaw No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
title | No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
title_full | No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
title_fullStr | No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
title_full_unstemmed | No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
title_short | No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
title_sort | no effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781578/ https://www.ncbi.nlm.nih.gov/pubmed/15770057 http://dx.doi.org/10.1155/S0962935104000572 |
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