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No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.

BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response. AIM: The hypothesis was verified as to whether ozonated autohemotherapy using an ozone dose in therapeutic range changes the plasma concentration of C-reactive protein and interleukin-6, markers of inflammation. METHODS: In a...

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Autores principales: Tylicki, Leszek, Biedunkiewicz, Bogdan, Rachon, Dominik, Nieweglowski, Tomasz, Hak, Lukasz, Chamienia, Andrzej, Debska-Slizien, Alicja, Aleksandrowicz, Ewa, Mysliwska, Jolanta, Rutkowski, Boleslaw
Formato: Texto
Lenguaje:English
Publicado: 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781578/
https://www.ncbi.nlm.nih.gov/pubmed/15770057
http://dx.doi.org/10.1155/S0962935104000572
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author Tylicki, Leszek
Biedunkiewicz, Bogdan
Rachon, Dominik
Nieweglowski, Tomasz
Hak, Lukasz
Chamienia, Andrzej
Debska-Slizien, Alicja
Aleksandrowicz, Ewa
Mysliwska, Jolanta
Rutkowski, Boleslaw
author_facet Tylicki, Leszek
Biedunkiewicz, Bogdan
Rachon, Dominik
Nieweglowski, Tomasz
Hak, Lukasz
Chamienia, Andrzej
Debska-Slizien, Alicja
Aleksandrowicz, Ewa
Mysliwska, Jolanta
Rutkowski, Boleslaw
author_sort Tylicki, Leszek
collection PubMed
description BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response. AIM: The hypothesis was verified as to whether ozonated autohemotherapy using an ozone dose in therapeutic range changes the plasma concentration of C-reactive protein and interleukin-6, markers of inflammation. METHODS: In a controlled, single-blind, cross-over study, 12 chronically hemodialyzed patients with peripheral arterial disease were exposed to nine sessions of autohemotherapy with blood exposure to oxygen as a control followed by nine sessions of ozonated autohemotherapy with an ozone concentration of 50 microg/ml. RESULTS: There was no statistical difference between C-reactive protein levels at baseline (1.53 +/- 1.01 mg/l), after nine sessions of control autohemotherapy (1.48 +/- 0.96 mg/l), and after nine sessions of ozonated autohemotherapy (1.55 +/- 0.84 mg/l). There was also no statistical difference between the interleukin-6 serum concentration at baseline (438 +/- 118 pg/ml), after nine sessions of control autohemotherapy (444 +/- 120 pg/ml), and after nine sessions of ozonated autohemotherapy (466 +/- 152 pg/ml). CONCLUSION: The results of this study suggest that ozonated autohemotherapy using an ozone concentration of 50 microg/ml does not induce an inflammatory response.
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spelling pubmed-17815782007-01-25 No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. Tylicki, Leszek Biedunkiewicz, Bogdan Rachon, Dominik Nieweglowski, Tomasz Hak, Lukasz Chamienia, Andrzej Debska-Slizien, Alicja Aleksandrowicz, Ewa Mysliwska, Jolanta Rutkowski, Boleslaw Mediators Inflamm Research Article BACKGROUND: Ozone as a strong oxidant may induce an inflammatory response. AIM: The hypothesis was verified as to whether ozonated autohemotherapy using an ozone dose in therapeutic range changes the plasma concentration of C-reactive protein and interleukin-6, markers of inflammation. METHODS: In a controlled, single-blind, cross-over study, 12 chronically hemodialyzed patients with peripheral arterial disease were exposed to nine sessions of autohemotherapy with blood exposure to oxygen as a control followed by nine sessions of ozonated autohemotherapy with an ozone concentration of 50 microg/ml. RESULTS: There was no statistical difference between C-reactive protein levels at baseline (1.53 +/- 1.01 mg/l), after nine sessions of control autohemotherapy (1.48 +/- 0.96 mg/l), and after nine sessions of ozonated autohemotherapy (1.55 +/- 0.84 mg/l). There was also no statistical difference between the interleukin-6 serum concentration at baseline (438 +/- 118 pg/ml), after nine sessions of control autohemotherapy (444 +/- 120 pg/ml), and after nine sessions of ozonated autohemotherapy (466 +/- 152 pg/ml). CONCLUSION: The results of this study suggest that ozonated autohemotherapy using an ozone concentration of 50 microg/ml does not induce an inflammatory response. 2004-12 /pmc/articles/PMC1781578/ /pubmed/15770057 http://dx.doi.org/10.1155/S0962935104000572 Text en
spellingShingle Research Article
Tylicki, Leszek
Biedunkiewicz, Bogdan
Rachon, Dominik
Nieweglowski, Tomasz
Hak, Lukasz
Chamienia, Andrzej
Debska-Slizien, Alicja
Aleksandrowicz, Ewa
Mysliwska, Jolanta
Rutkowski, Boleslaw
No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
title No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
title_full No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
title_fullStr No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
title_full_unstemmed No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
title_short No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
title_sort no effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781578/
https://www.ncbi.nlm.nih.gov/pubmed/15770057
http://dx.doi.org/10.1155/S0962935104000572
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