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Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disorder, with a considerable genetic influence on susceptibility and disease course. Cytokines play an important role in MS pathophysiology, and genes encoding various cytokines are logical candidates to assess possible associations with MS susce...

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Detalles Bibliográficos
Autores principales: Schrijver, Hans M, van As, Jaco, Crusius, J Bart A, Dijkstra, Christien D, Uitdehaag, Bernard M J
Formato: Texto
Lenguaje:English
Publicado: 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781595/
https://www.ncbi.nlm.nih.gov/pubmed/12775358
http://dx.doi.org/10.1080/0962933031000097691

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