The role of X-chromosome inactivation in female predisposition to autoimmunity

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INTRODUCTION: A reduction in the sex ratio (male : female) is characteristic of most autoimmune disorders. The increased prevalence in females ranges from a modest 2:1 for multiple sclerosis [1], to approximately 10:1 for systemic lupus erythematosus [2]. This tendency toward autoimmunity in females...

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Detalles Bibliográficos
Autores principales: Chitnis, Smita, Monteiro, Joanita, Glass, David, Apatoff, Brian, Salmon, Jane, Concannon, Patrick, Gregersen, Peter K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17816/
https://www.ncbi.nlm.nih.gov/pubmed/11056674
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