Basal secretion of lysozyme from human airways in vitro.

The aim of this study was to examine the basal release of lysozyme from isolated human lung tissues. Measurements of lysozyme in the fluids derived from lung preparations were performed using a rate-of-lysis assay subsequent to acidification of the biological samples. Lysozyme released from bronchia...

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Detalles Bibliográficos
Autores principales: Roger, P, Gascard, J P, de Montpreville, V T, Brink, C
Formato: Texto
Lenguaje:English
Publicado: 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781815/
https://www.ncbi.nlm.nih.gov/pubmed/10815621
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author Roger, P
Gascard, J P
de Montpreville, V T
Brink, C
author_facet Roger, P
Gascard, J P
de Montpreville, V T
Brink, C
author_sort Roger, P
collection PubMed
description The aim of this study was to examine the basal release of lysozyme from isolated human lung tissues. Measurements of lysozyme in the fluids derived from lung preparations were performed using a rate-of-lysis assay subsequent to acidification of the biological samples. Lysozyme released from bronchial preparations into fluids was greater than that observed for parenchymal tissues. The lysozyme quantities detected in bronchial fluids were not modified by removal of the surface epithelium. Furthermore, the quantities of lysozyme in bronchial fluids was correlated with the size of the bronchial preparations. These results suggest that the lysozyme was principally secreted by the human bronchi (submucosal layer) rather than by parenchyma tissues and that a greater release was observed in the proximal airways.
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spelling pubmed-17818152007-01-25 Basal secretion of lysozyme from human airways in vitro. Roger, P Gascard, J P de Montpreville, V T Brink, C Mediators Inflamm Research Article The aim of this study was to examine the basal release of lysozyme from isolated human lung tissues. Measurements of lysozyme in the fluids derived from lung preparations were performed using a rate-of-lysis assay subsequent to acidification of the biological samples. Lysozyme released from bronchial preparations into fluids was greater than that observed for parenchymal tissues. The lysozyme quantities detected in bronchial fluids were not modified by removal of the surface epithelium. Furthermore, the quantities of lysozyme in bronchial fluids was correlated with the size of the bronchial preparations. These results suggest that the lysozyme was principally secreted by the human bronchi (submucosal layer) rather than by parenchyma tissues and that a greater release was observed in the proximal airways. 1999 /pmc/articles/PMC1781815/ /pubmed/10815621 Text en
spellingShingle Research Article
Roger, P
Gascard, J P
de Montpreville, V T
Brink, C
Basal secretion of lysozyme from human airways in vitro.
title Basal secretion of lysozyme from human airways in vitro.
title_full Basal secretion of lysozyme from human airways in vitro.
title_fullStr Basal secretion of lysozyme from human airways in vitro.
title_full_unstemmed Basal secretion of lysozyme from human airways in vitro.
title_short Basal secretion of lysozyme from human airways in vitro.
title_sort basal secretion of lysozyme from human airways in vitro.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781815/
https://www.ncbi.nlm.nih.gov/pubmed/10815621
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AT gascardjp basalsecretionoflysozymefromhumanairwaysinvitro
AT demontprevillevt basalsecretionoflysozymefromhumanairwaysinvitro
AT brinkc basalsecretionoflysozymefromhumanairwaysinvitro

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