Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?

Oxidative damage is involved in the pathogenic process of idiopathic chronic inflammatory bowel disease. Although specific intervention in the oxidative cascade showed promising results in animal models and preliminary patient trials, the clinical efficacy of antioxidants still has to be established...

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Detalles Bibliográficos
Autores principales: Kruidenier, L, Verspaget, H W
Formato: Texto
Lenguaje:English
Publicado: 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781836/
https://www.ncbi.nlm.nih.gov/pubmed/9705602
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author Kruidenier, L
Verspaget, H W
author_facet Kruidenier, L
Verspaget, H W
author_sort Kruidenier, L
collection PubMed
description Oxidative damage is involved in the pathogenic process of idiopathic chronic inflammatory bowel disease. Although specific intervention in the oxidative cascade showed promising results in animal models and preliminary patient trials, the clinical efficacy of antioxidants still has to be established. Mucosa protection, for example by dietary fatty acids, seems to attenuate the intestinal inflammatory process as well but awaits definite clinical proof for the treatment of inflammatory bowel disease.
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spelling pubmed-17818362007-01-25 Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease? Kruidenier, L Verspaget, H W Mediators Inflamm Research Article Oxidative damage is involved in the pathogenic process of idiopathic chronic inflammatory bowel disease. Although specific intervention in the oxidative cascade showed promising results in animal models and preliminary patient trials, the clinical efficacy of antioxidants still has to be established. Mucosa protection, for example by dietary fatty acids, seems to attenuate the intestinal inflammatory process as well but awaits definite clinical proof for the treatment of inflammatory bowel disease. 1998 /pmc/articles/PMC1781836/ /pubmed/9705602 Text en
spellingShingle Research Article
Kruidenier, L
Verspaget, H W
Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
title Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
title_full Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
title_fullStr Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
title_full_unstemmed Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
title_short Antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
title_sort antioxidants and mucosa protectives: realistic therapeutic options in inflammatory bowel disease?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781836/
https://www.ncbi.nlm.nih.gov/pubmed/9705602
work_keys_str_mv AT kruidenierl antioxidantsandmucosaprotectivesrealistictherapeuticoptionsininflammatoryboweldisease
AT verspagethw antioxidantsandmucosaprotectivesrealistictherapeuticoptionsininflammatoryboweldisease

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