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Rheumatoid synovial CD4(+) T cells exhibit a reduced capacity to differentiate into IL-4-producing T-helper-2 effector cells
CD4(+) memory T cells (Tm) from rheumatoid arthritis peripheral blood (RAPB) or peripheral blood from normal donors produced IL-2, whereas fewer cells secreted IFN-γ or IL-4 after a brief stimulation. RAPB Tm contained significantly more IFN-γ producers than normal cells. Many rheumatoid arthritis (...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17825/ https://www.ncbi.nlm.nih.gov/pubmed/11178127 |