Rheumatoid synovial CD4(+) T cells exhibit a reduced capacity to differentiate into IL-4-producing T-helper-2 effector cells

CD4(+) memory T cells (Tm) from rheumatoid arthritis peripheral blood (RAPB) or peripheral blood from normal donors produced IL-2, whereas fewer cells secreted IFN-γ or IL-4 after a brief stimulation. RAPB Tm contained significantly more IFN-γ producers than normal cells. Many rheumatoid arthritis (...

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Detalles Bibliográficos
Autores principales: Davis, Laurie S, Cush, John J, Schulze-Koops, Hendrik, Lipsky, Peter E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17825/
https://www.ncbi.nlm.nih.gov/pubmed/11178127

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