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Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens
BACKGROUND: In both schizophrenia and addiction, pathological changes in dopamine release appear to induce alterations in the circuitry of the nucleus accumbens that affect coordinated thought and motivation. Dopamine acts principally on medium-spiny GABA neurons, which comprise 95% of accumbens neu...
Autores principales: | Mizuno, Takeo, Schmauss, Claudia, Rayport, Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783657/ https://www.ncbi.nlm.nih.gov/pubmed/17239247 http://dx.doi.org/10.1186/1471-2202-8-8 |
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