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A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

BACKGROUND: The apparent dominant model of colorectal cancer (CRC) inheritance in several large families, without mutations in known CRC susceptibility genes, suggests the presence of so far unidentified genes with strong or moderate effect on the development of CRC. Linkage analysis could lead to i...

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Detalles Bibliográficos
Autores principales:	Middeldorp, Anneke, Jagmohan-Changur, Shantie, Helmer, Quinta, van der Klift, Heleen M, Tops, Carli MJ, Vasen, Hans FA, Devilee, Peter, Morreau, Hans, Houwing-Duistermaat, Jeanine J, Wijnen, Juul T, van Wezel, Tom
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784097/ https://www.ncbi.nlm.nih.gov/pubmed/17222328 http://dx.doi.org/10.1186/1471-2407-7-6

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