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Importance of A-loop complementarity with tRNA(His )anticodon for continued selection of tRNA(His )as the HIV reverse transcription primer
BACKGROUND: Human immunodeficiency virus (HIV-1) preferentially selects tRNA(Lys,3 )as the primer for reverse transcription. HIV-1 can be forced to select alternative tRNAs through mutation in the primer-binding site (PBS) and a region upstream of the PBS designated as the A-loop. Alteration of the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1785369/ https://www.ncbi.nlm.nih.gov/pubmed/17214904 http://dx.doi.org/10.1186/1743-422X-4-4 |