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Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease
BACKGROUND: Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been directly associated with inflammation and the production of free radicals are the prostaglandin 13,14-dihydro...
Autores principales: | Casadesus, Gemma, Smith, Mark A, Basu, Samar, Hua, Jing, Capobianco, Dae E, Siedlak, Sandra L, Zhu, Xiongwei, Perry, George |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1785381/ https://www.ncbi.nlm.nih.gov/pubmed/17241462 http://dx.doi.org/10.1186/1750-1326-2-2 |
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