Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System

The in vivo effect of trimethyltin chloride (Me(3)SnCl), free base meso-tetrakis(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin (R′(4)PH(2)) and their equimolar mixture, on the enzymatic activity of catalase (CAT), superoxide dismutase (SOD), and on the total content of free sulfhydryl groups has been...

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Detalles Bibliográficos
Autores principales: Milaeva, Elena R., Tyurin, Vladimir Yu., Gracheva, Yulia A., Dodochova, Margarita A., Pustovalova, Lydia M., Chernyshev, Victor N.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794078/
https://www.ncbi.nlm.nih.gov/pubmed/17497013
http://dx.doi.org/10.1155/BCA/2006/64927
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author Milaeva, Elena R.
Tyurin, Vladimir Yu.
Gracheva, Yulia A.
Dodochova, Margarita A.
Pustovalova, Lydia M.
Chernyshev, Victor N.
author_facet Milaeva, Elena R.
Tyurin, Vladimir Yu.
Gracheva, Yulia A.
Dodochova, Margarita A.
Pustovalova, Lydia M.
Chernyshev, Victor N.
author_sort Milaeva, Elena R.
collection PubMed
description The in vivo effect of trimethyltin chloride (Me(3)SnCl), free base meso-tetrakis(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin (R′(4)PH(2)) and their equimolar mixture, on the enzymatic activity of catalase (CAT), superoxide dismutase (SOD), and on the total content of free sulfhydryl groups has been studied in rat liver and kidney. It was demonstrated that the simultaneous treatment of tested animals with the combination of Me(3)SnCl and R′(4)PH(2) reduced the toxic impact of Me(3)SnCl.
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spelling pubmed-17940782007-02-12 Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System Milaeva, Elena R. Tyurin, Vladimir Yu. Gracheva, Yulia A. Dodochova, Margarita A. Pustovalova, Lydia M. Chernyshev, Victor N. Bioinorg Chem Appl Research Article The in vivo effect of trimethyltin chloride (Me(3)SnCl), free base meso-tetrakis(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin (R′(4)PH(2)) and their equimolar mixture, on the enzymatic activity of catalase (CAT), superoxide dismutase (SOD), and on the total content of free sulfhydryl groups has been studied in rat liver and kidney. It was demonstrated that the simultaneous treatment of tested animals with the combination of Me(3)SnCl and R′(4)PH(2) reduced the toxic impact of Me(3)SnCl. Hindawi Publishing Corporation 2006 2006-12-27 /pmc/articles/PMC1794078/ /pubmed/17497013 http://dx.doi.org/10.1155/BCA/2006/64927 Text en Copyright © 2006 Elena R. Milaeva et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Milaeva, Elena R.
Tyurin, Vladimir Yu.
Gracheva, Yulia A.
Dodochova, Margarita A.
Pustovalova, Lydia M.
Chernyshev, Victor N.
Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
title Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
title_full Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
title_fullStr Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
title_full_unstemmed Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
title_short Protective Effect of Meso-Tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the In Vivo Impact of Trimethyltin Chloride on the Antioxidative Defense System
title_sort protective effect of meso-tetrakis-(3,5-di-tert-butyl-4-hydroxyphenyl)porphyrin on the in vivo impact of trimethyltin chloride on the antioxidative defense system
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794078/
https://www.ncbi.nlm.nih.gov/pubmed/17497013
http://dx.doi.org/10.1155/BCA/2006/64927
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