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Pathophysiology of focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease...
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Formato: | Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794138/ https://www.ncbi.nlm.nih.gov/pubmed/17216262 http://dx.doi.org/10.1007/s00467-006-0357-2 |
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author | Reidy, Kimberly Kaskel, Frederick J. |
author_facet | Reidy, Kimberly Kaskel, Frederick J. |
author_sort | Reidy, Kimberly |
collection | PubMed |
description | Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS. |
format | Text |
id | pubmed-1794138 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-17941382007-02-21 Pathophysiology of focal segmental glomerulosclerosis Reidy, Kimberly Kaskel, Frederick J. Pediatr Nephrol Educational Feature Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS. Springer Berlin Heidelberg 2007-03-01 2007 /pmc/articles/PMC1794138/ /pubmed/17216262 http://dx.doi.org/10.1007/s00467-006-0357-2 Text en © IPNA 2007 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Educational Feature Reidy, Kimberly Kaskel, Frederick J. Pathophysiology of focal segmental glomerulosclerosis |
title | Pathophysiology of focal segmental glomerulosclerosis |
title_full | Pathophysiology of focal segmental glomerulosclerosis |
title_fullStr | Pathophysiology of focal segmental glomerulosclerosis |
title_full_unstemmed | Pathophysiology of focal segmental glomerulosclerosis |
title_short | Pathophysiology of focal segmental glomerulosclerosis |
title_sort | pathophysiology of focal segmental glomerulosclerosis |
topic | Educational Feature |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794138/ https://www.ncbi.nlm.nih.gov/pubmed/17216262 http://dx.doi.org/10.1007/s00467-006-0357-2 |
work_keys_str_mv | AT reidykimberly pathophysiologyoffocalsegmentalglomerulosclerosis AT kaskelfrederickj pathophysiologyoffocalsegmentalglomerulosclerosis |