Cargando…

Pathophysiology of focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease...

Descripción completa

Detalles Bibliográficos
Autores principales: Reidy, Kimberly, Kaskel, Frederick J.
Formato: Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794138/
https://www.ncbi.nlm.nih.gov/pubmed/17216262
http://dx.doi.org/10.1007/s00467-006-0357-2
_version_ 1782132151127375872
author Reidy, Kimberly
Kaskel, Frederick J.
author_facet Reidy, Kimberly
Kaskel, Frederick J.
author_sort Reidy, Kimberly
collection PubMed
description Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS.
format Text
id pubmed-1794138
institution National Center for Biotechnology Information
language English
publishDate 2007
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-17941382007-02-21 Pathophysiology of focal segmental glomerulosclerosis Reidy, Kimberly Kaskel, Frederick J. Pediatr Nephrol Educational Feature Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS. Springer Berlin Heidelberg 2007-03-01 2007 /pmc/articles/PMC1794138/ /pubmed/17216262 http://dx.doi.org/10.1007/s00467-006-0357-2 Text en © IPNA 2007 This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Educational Feature
Reidy, Kimberly
Kaskel, Frederick J.
Pathophysiology of focal segmental glomerulosclerosis
title Pathophysiology of focal segmental glomerulosclerosis
title_full Pathophysiology of focal segmental glomerulosclerosis
title_fullStr Pathophysiology of focal segmental glomerulosclerosis
title_full_unstemmed Pathophysiology of focal segmental glomerulosclerosis
title_short Pathophysiology of focal segmental glomerulosclerosis
title_sort pathophysiology of focal segmental glomerulosclerosis
topic Educational Feature
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794138/
https://www.ncbi.nlm.nih.gov/pubmed/17216262
http://dx.doi.org/10.1007/s00467-006-0357-2
work_keys_str_mv AT reidykimberly pathophysiologyoffocalsegmentalglomerulosclerosis
AT kaskelfrederickj pathophysiologyoffocalsegmentalglomerulosclerosis