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Kv1.1 null mice have enlarged hippocampus and ventral cortex

BACKGROUND: Mutations in the Shaker-like voltage-gated potassium channel Kv1.1 are known to cause episodic ataxia type 1 and temporal lobe epilepsy. Mice that express a malfunctional, truncated Kv1.1 (BALB/cByJ-Kv1.1(mceph/mceph)) show a markedly enlarged hippocampus and ventral cortex in adulthood....

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Detalles Bibliográficos
Autores principales: Persson, Ann-Sophie, Westman, Eric, Wang, Fu-Hua, Khan, Firoj Hossain, Spenger, Christian, Lavebratt, Catharina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794250/
https://www.ncbi.nlm.nih.gov/pubmed/17250763
http://dx.doi.org/10.1186/1471-2202-8-10