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Robustness Can Evolve Gradually in Complex Regulatory Gene Networks with Varying Topology
The topology of cellular circuits (the who-interacts-with-whom) is key to understand their robustness to both mutations and noise. The reason is that many biochemical parameters driving circuit behavior vary extensively and are thus not fine-tuned. Existing work in this area asks to what extent the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794322/ https://www.ncbi.nlm.nih.gov/pubmed/17274682 http://dx.doi.org/10.1371/journal.pcbi.0030015 |