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Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A(3 )adenosine receptor expression

Methotrexate (MTX) exerts an anti-inflammatory effect via its metabolite adenosine, which activates adenosine receptors. The A(3 )adenosine receptor (A(3)AR) was found to be highly expressed in inflammatory tissues and peripheral blood mononuclear cells (PBMCs) of rats with adjuvant-induced arthriti...

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Detalles Bibliográficos
Autores principales: Ochaion, Avivit, Bar-Yehuda, Sara, Cohn, Shira, Del Valle, Luis, Perez-Liz, Georginia, Madi, Lea, Barer, Faina, Farbstein, Motti, Fishman-Furman, Sari, Reitblat, Tatiana, Reitblat, Alexander, Amital, Howard, Levi, Yair, Molad, Yair, Mader, Reuven, Tishler, Moshe, Langevitz, Pnina, Zabutti, Alexander, Fishman, Pnina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794513/
https://www.ncbi.nlm.nih.gov/pubmed/17101059
http://dx.doi.org/10.1186/ar2078