Cargando…
Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A(3 )adenosine receptor expression
Methotrexate (MTX) exerts an anti-inflammatory effect via its metabolite adenosine, which activates adenosine receptors. The A(3 )adenosine receptor (A(3)AR) was found to be highly expressed in inflammatory tissues and peripheral blood mononuclear cells (PBMCs) of rats with adjuvant-induced arthriti...
Autores principales: | Ochaion, Avivit, Bar-Yehuda, Sara, Cohn, Shira, Del Valle, Luis, Perez-Liz, Georginia, Madi, Lea, Barer, Faina, Farbstein, Motti, Fishman-Furman, Sari, Reitblat, Tatiana, Reitblat, Alexander, Amital, Howard, Levi, Yair, Molad, Yair, Mader, Reuven, Tishler, Moshe, Langevitz, Pnina, Zabutti, Alexander, Fishman, Pnina |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794513/ https://www.ncbi.nlm.nih.gov/pubmed/17101059 http://dx.doi.org/10.1186/ar2078 |
Ejemplares similares
-
The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis
por: Fishman, Pnina, et al.
Publicado: (2006) -
Inhibition of IL-17 and IL-23 in Human Keratinocytes by the A(3) Adenosine Receptor Agonist Piclidenoson
por: Cohen, Shira, et al.
Publicado: (2018) -
A(3) Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action
por: Cohen, Shira, et al.
Publicado: (2014) -
The A3 adenosine receptor agonist, namodenoson, ameliorates non-alcoholic steatohepatitis in mice
por: Fishman, Pnina, et al.
Publicado: (2019) -
Targeting the A(3) adenosine receptor to treat cytokine release syndrome in cancer immunotherapy
por: Cohen, Shira, et al.
Publicado: (2019)