Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health

Juvenile idiopathic arthritis (JIA) is a heterogeneous autoimmune disease characterized by chronic joint inflammation. Knowing which antigens drive the autoreactive T-cell response in JIA is crucial for the understanding of disease pathogenesis and additionally may provide targets for antigen-specif...

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Detalles Bibliográficos
Autores principales: Kamphuis, Sylvia, Hrafnkelsdóttir, Kolbrún, Klein, Mark R, de Jager, Wilco, Haverkamp, Margje H, van Bilsen, Jolanda HM, Albani, Salvatore, Kuis, Wietse, Wauben, Marca HM, Prakken, Berent J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794523/
https://www.ncbi.nlm.nih.gov/pubmed/17129378
http://dx.doi.org/10.1186/ar2088

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