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Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues
BACKGROUND: Selenocysteine (Sec) is co-translationally inserted into protein in response to UGA codons. It occurs in oxidoreductase active sites and often is catalytically superior to cysteine (Cys). However, Sec is used very selectively in proteins and organisms. The wide distribution of Sec and it...
Autores principales: | Zhang, Yan, Romero, Hector, Salinas, Gustavo, Gladyshev, Vadim N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794560/ https://www.ncbi.nlm.nih.gov/pubmed/17054778 http://dx.doi.org/10.1186/gb-2006-7-10-r94 |
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